Diphtheria and Tetanus Toxoids and Pertussis Vaccine
Adsorbed. For Active Immunization against Diphtheria,
Tetanus and Whooping Cough.
Description. Diphtheria and Tetanus Toxoids and Pertussis Vaccine Adsorbed (DPT Vaccine Adsorbed) as supplied by Connaught Laboratories Limited, is sterile, cloudy, uniform suspension of diphtheria and tetanus toxoids and pertussis vaccine adsorbed on aluminium phosphate and suspended in isotonic sodium chloride solution.
This vaccine fulfils the WHO requirements Diphtheria Toxoid, Tetanus Toxoid and Pertussis Vaccine.
Indications. DPT Vaccine Adsorbed is indicated for the primary immunization of infants at or above the age of two months, and of children through 6 years of age against diphtheria, tetanus and whooping cough.
Contraindications. DPT Vaccine Adsorbed should not be administered to infants or children with fever, or other evidence of acute illness or infection. The presence of an evolving or changing neurologic disorder is a contraindication to receipt of this vaccine. A second or third DPT injection should not be given to a child who has suffered a severe adverse reaction to the previous dose. The pertussis component should be omitted and diphtheria and tetanus immunization completed.
Elective immunization of individuals over б months of age should be deferred during an outbreak of poliomyelitis.
DPT Vaccine Adsorbed should not be administered to children over б years of age or to adults because of the danger of reactions to diphtheria toxoid or to pertussis vaccine and because pertussis is less severe in these age groups than in infants and young children.
Dosage. For primary immunization of infants and pre-school children through 6 years of age, it is recommended that three intramuscular injections of 0.5 ml be administered with an interval of four to eight weeks between doses. For a lasting immunization effect, a fourth injection of 0.5 ml is essential approximately one year following the third dose.
Administration. The vaccine should be administered by intramuscular injection. The musculus vastus lateralis (mid-thigh laterally) is the preferred injection site for infants. The site of injection shoud be prepared with a suitable antiseptic. Do not inject intravenously. Each injection of the primary immunization series should be made into a different area (site). If sterile disposable syringes and needles are not used, syringes and needles should be sterilized in an autoclave at 121°С for 30 minutes. Failing that, they should be boiled for at least 20 minutes. Care should be taken to maintain sterility until used.
Storage. Diphtheria and Tetanus Toxoids and Pertussis Vaccine Adsorbed shouls be stored and transported at a temperature between 2° and 8°C (35° and 46°F). Do not freeze. Product which has been exposed to freezing should not be used. When using a multi-dose vial, it is recommended that partially used vials be discarded at the end of the day.
Complete the following sentences using the key words, given below:
1. Diphtheria and Tetanus Toxoids and Pertussis Vaccine Adsorbed (DPT Vaccine Adsorbed) as supplied by …, is sterile, cloudy, uniform suspension of diphtheria and tetanus toxoids and pertussis vaccine absorbed or aluminium phosphate and …
b) one year
g) Vastus lateralis
h) Connaught Laboratories Limited
1. Connaught Laboratories Limited
6. one year
8. Vastus lateralis
1. What Connaught Laboratories is DPT Adsorbed supplied by?
2. What do you know about the ingredients of this medicine?
3. Say anything you know about the indications of DPT Vaccine.
4. Comment upon the contraindications of the medicine under review.
5. The presence of an evolving or chanding neurologic disorder is a contraindication to receipt of this vaccine, isn’t it?
6. What component should be omitted if the child nas a severe adverse reaction to the previous.
7. Elective immunization of individuals over 6 months of age should be deferred during an outbreak of poliomyelitis, shouldn’t it?
8. Should DPT Vaccine Adsorbed not be administered to in fants and children with fever or to adults?
9. What did you get to know about the dosage of DPT Vaccine?
10. Is it recommended that 3, or 4 intramuscular injections of 0,5 ml be administered with an internal of four to eight weeks between doses.
11. Is a fourth injection of 0,5 ml essential approximateri one year following the third dose?
12. How should the vaccine be administered?
13. What should be administered by intramuscular injection?
14. What is the preferred site of injection for infants?
15. In to what area should each injection of the primary immunization series be made?