Long-term sleep deprivation caused deeper changes of functional state of the studied processes but during the 2 weeks` period after the end of the effect, they were restored till the level of intact animals. The effect of two factors potentiated the revealed changes.
Irrespective of the conditions of the experiment more expressed changes in the functional state of stress-realizing systems have been observed in the studied structures of male rats.
Sleep deprivation in mature rats obtained from the irradiated parents resulted in fast exhaustion of the state of stress-realizing systems; its restoration till the level of the intact animals was not observed till the end of the experiment.
Key words: - irradiation, stress, pituitary gland, hypothalamus, adrenals, blood, urine, descendants.